HA Filler

Beatrice Dermdeep

Volume Restoration and Wrinkle Correction

A cross-linked sodium hyaluronate filler designed for facial tissue volumising. Through full, even filling and excellent tissue integration, it restores natural fullness with a balanced dynamic and static appearance.

  • Facial volume restoration — enhances overall fullness
  • Volumising fill — natural in motion, soft at rest
  • High tissue integration — stable, minimal migration
  • High biocompatibility — natural, safe, suited to larger body areas
HA Content 20 mg/mL
Volume 1.0 mL
Presentation PFS
Store 4–25 °C, protect from sunlight
Full Specifications

Technical Data at a Glance.

CompositionCross-linked sodium hyaluronate
HA Content20 mg/mL
Lidocaine ContentNone
Volume1.0 mL per syringe
PresentationPre-filled syringe
Dynamic Viscosity118,000 mPa·s
Elastic Modulus G'201 Pa (1 Hz)
Particle Size150–200 μm
BDDE Residue≤ 0.8 μg/g
Needle27G, 12 mm × 2
IndicationsFor facial volume loss and insufficient contour fullness — restoring sunken areas caused by ageing or structural loss, such as the nasolabial folds, temples, forehead and lips, as well as localised body volume supplementation.
Duration6–9 months
StorageStore 4–25 °C · protect from sunlight · do not freeze

Mechanism of Action

Diagram showing deep dermal or subcutaneous placement of cross-linked hyaluronic acid for facial volume restoration
Deep Volumising Support

Following deep subcutaneous or supraperiosteal injection, cross-linked sodium hyaluronate provides localised volumising support to immediately improve facial depressions and wrinkles, delivering a natural and balanced enhancement.

Technical Advantage

Three complementary technologies support uniform structure, natural integration and stable volumising performance.

Comparison illustrating UNICROSS technology and a more uniform cross-linked hyaluronic acid network

UNICROSS Cross-linking Technology

Jointly developed by CIMM and Germany's NMI, UNICROSS uses a patented solvent to promote uniform dispersion of HA molecules, improving cross-linking efficiency while reducing cross-linker usage and residue. This enhances product safety and helps lower the risk of potential adverse reactions.

Fewer semi-free cross-linking bonds help form a more uniform and stable cross-linked network, improving structural stability for longer-lasting filling and shaping performance.

Microscopy comparison showing a homogeneous single-phase hyaluronic acid gel structure

Single-Phase Homogeneous Gel

A uniform, fine gel structure offers improved consistency and tissue compatibility, supporting a natural filling result.

Enhanced cohesiveness and rheological stability help the gel remain in place after injection, delivering more stable long-term results.

Rheological Performance Test

High cohesiveness enables the gel to resist deformation under external force, maintaining a stable gel structure and filling shape. This helps reduce post-injection deformation and migration, delivering more stable, natural and long-lasting filling results.

Clinical Case

Before & After

Real patient photography from a Beatrice Dermdeep treatment — drag the divider to compare.

After — Beatrice Dermdeep clinical case: full face Before — Beatrice Dermdeep clinical case: full face
Before After

Nasolabial Fold Volume Restoration

A Beatrice Dermdeep treatment for the nasolabial folds using 2 mL of cross-linked sodium hyaluronate.

  • SubjectFemale · 35 years
  • RegionNasolabial folds
  • ProductBeatrice Dermdeep
  • Dosage2 mL

Illustrative clinical case — individual results may vary.

Clinical Evidence

Measured Results.

At 24 weeks post-treatment, the effective improvement rate for moderate-to-severe nasolabial wrinkles reached 94.95%.

94.95%
24-Week Efficacy — Nasolabial Wrinkles

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