HA Filler

Beatrice Derm

Moderate to Severe Superficial Wrinkles (Face & Neck)

A lightly cross-linked sodium hyaluronate filler containing lidocaine, designed for moderate to severe superficial wrinkles on the face and neck. Superior viscoelasticity delivers natural, smooth support with more lasting, immediate improvement.

  • Moderate-to-severe neck wrinkles & facial superficial wrinkles — effectively improved
  • Superior viscoelasticity & tissue support — smooths wrinkles naturally
  • Contains lidocaine — enhanced injection comfort
  • More stable structure — longer-lasting results
HA Content 15 mg/mL
Volume 1.25 mL
Presentation PFS
Store 4–25 °C, protect from sunlight
Full Specifications

Technical Data at a Glance.

CompositionCross-linked sodium hyaluronate, lidocaine hydrochloride
HA Content15 mg/mL
Lidocaine Content3 mg/mL
Volume1.25 mL per syringe
PresentationPre-filled syringe
Dynamic Viscosity23,860 mPa·s
Elastic Modulus G'46.09 Pa (0.1 Hz)
Particle Size125 μm
BDDE Residue≤ 0.4 μg/g
Needle30G, 13 mm × 2
IndicationsFor wrinkle improvement on the face and neck. On the neck it suits moderate to moderate-to-severe wrinkles such as prominent neck lines; on the face it targets deeper superficial wrinkles — crow's feet, perioral lines, lip lines and wrinkles deepened by dynamic movement. For those needing both wrinkle correction and foundational support.
Duration3–6 months
StorageStore 4–25 °C · protect from sunlight · do not freeze

Mechanism of Action

Diagram showing the filling and support effect of lightly cross-linked hyaluronic acid for moderate to severe superficial wrinkles
Localised Filling & Support

Following subcutaneous injection, Derm uses the localised filling and support properties of lightly cross-linked sodium hyaluronate to smooth moderate to severe superficial wrinkles on the face and neck, delivering a natural and lasting improvement.

Technical Advantage

Molecular illustration of H-Unlock cross-linking technology reducing hydrogen-bond interactions in hyaluronic acid gel

H-Unlock Cross-linking Technology

By disrupting selected hydrogen bonds between HA molecules, H-Unlock reduces intermolecular interactions, allowing the gel to extend and spread more evenly for refined treatment of fine facial and neck lines.

Because the cross-link structure and degree of cross-linking remain unchanged, product longevity is maintained to support lasting filling performance.

Comparison showing lower gel swelling for a more natural immediate result after injection

Optimised Swelling Control

Disrupting selected hydrogen bonds lowers gel swelling, helping reduce early post-injection oedema and supporting a more natural immediate result.

Clinical Cases

Before & After

Two real patient cases treated with Beatrice Derm — select a case, then drag the divider to compare.

After — Beatrice Derm clinical case: neck, 60 days Before — Beatrice Derm clinical case: neck
Before After

Neck Fine-Line Smoothing

A Beatrice Derm treatment of the neck using 2.5 mL.

  • SubjectFemale · 29 years
  • RegionNeck
  • ProductBeatrice Derm
  • Dosage2.5 mL

Illustrative clinical case — individual results may vary.

Clinical Evidence

Measured Results.

At 60 days post-treatment, the effective improvement rate for moderate-to-severe neck wrinkles reached 91.75%.

91.75%
60-Day Efficacy — Neck Wrinkles

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